Another difference between art and design is how the messages of each are interpreted by their respective audiences.Although an artist sets out to convey a viewpoint or emotion, that is not to say that the viewpoint or emotion has a single meaning.Art connects with people in different ways, because itâ€™s interpreted differently.Da Vinciâ€™s Mona Lisa has been interpreted and discussed for many years. Just why is she smiling? Scientists say itâ€™s an illusion created by your peripheral vision. Romantics say she is in love. Skeptics say there is no reason. None of them are wrong.