BIO 350 – Patterns in Human Inheritance Traits

| April 14, 2018

ExperimentHUMAN GENETICSHumanGeneticsMargaret E. Vorndam,M.S.Version 42-0068-0001LAB REPORT ASSISTANTThis document is not meant to be a substitute for a formal laboratory report. The LabReport Assistant is simply a summary of the experiment’s questions, diagrams ifneeded, and data tables that should be addressed in a formal lab report. The intent is tofacilitate student’s writing of lab reports by providing this information in an editable filewhich can be sent to an instructorOBSERVATIONSData Table 1: Single-gene Traits of a Selected PopulationSubject # >1XX Female23456789101112XXXY MaleFF,Ff = unattachedff = attachedffRR,Rr = rollerRrr = can’t rollSS,Ss = straight thumbss = bent thumbssMM,Mm = hairmm = no hairmmTT,Tt = left on topTtt = right on topLL,Ll = two tendonsLll = three tendonsm265©Hands-On Labs,131415TotalExperimentHUMAN GENETICSExercise 1: Patterns in Human Inheritance TraitsQUESTIONSA. What observations can be made about the collected and charted data?B. Are any two people exactly the same? If so, how closely are they related?C. Is your hypothesis supported by the findings? What statistical tool might help youto make this decision?D. In the totals that you recorded in Table 1, did you find that the number of dominantphenotypes were greater than, equal to, or less than the recessive phenotypes?E. Can you explain what possible genotypes are suggested by this pattern? Doesthis vary by trait?m12©Hands-On Labs,ExperimentHUMAN GENETICSF. Would you expect this outcome? Why or whynot?G. How would changing the level of the mapped traits affect the chart? For instance, ifthe alleles for male or female were on the outer rim of the chart, rather than in themiddle, how would the pattern observed differ from Figure 10-1?H. List several other traits that humans have that are governed bygenetics.I. Would your data vary if you went to another part of the world, for instance,China?J.Why might collected data show different patterns for different culturalpopulations?K. Would you expect that the pattern would be different if collected 100 years agoinstead of today? Why or why not?m13©Hands-On Labs,ExperimentHUMAN GENETICSL.If you had percentages of dominant and recessive genes present for the totalnumber of alleles of a trait for the entire world, would you expect that percentage tochange over 100 years? Why or why not?Exercise 2: Human Chromosomes and theHumanGenomeProjectRESULTSReport on your findings. Your report should be limited to a page in length and mayincorporate the outline of research points above.m14©Hands-On Labs,ExperimentmHUMAN GENETICS15©Hands-On Labs,ExperimentHUMAN GENETICSQUESTIONSA.What is the purpose of thisexercise?B.What is the prognosis on genetic diseases in the future? Do you believe thatmicrosurgery to “fix” chromosomal aberrations will some day prevent the diseases thatare listed in the List of Genetically Mediated Diseases in Humans?m16©Hands-On Labs,ExperimentHUMAN GENETICSLABO RATORY SUMMARYWhat have you learned from doing this laboratory?REFERENCESCopyright © 2008 by Margaret E. Vorndam, 1413 County Road 671, Rye, CO 81069m17©Hands-On Labs,

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